The dilemmas of the working mum...

Career or family? Can one have both? I have a great career opportunity right in front of me, but it will mean returning to work full time *sigh*. If I turn it down, I may never get the chance again, but then if I take it, I'll never get the chance to spend the next few months of their pre-school lives with my children again. Have to make a decision by Friday and I am seriously torn. What to do?